| ncRNA name | EPOR siRNA |
| ncRNA Category | siRNA |
| Disease name | retinopathy of prematurity (ROP) |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal microvascular endothelial cells (HRMVECs) |
| Methods | siRNA transfection, qPCR, Western blot |
| Expression pattern | associated |
| Functional description | Knockdown of EPOR by siRNA transfection reduced VEGF-induced EC proliferation in association with reduced p-VEGFR2 and p-STAT3; however, inhibition of VEGFR2 activation by siRNA transfection or semaxanib (SU5416) abolished VEGFA-induced proliferation of ECs and phosphorylation of VEGFR2, EPOR, and STAT3. |
| PubMed ID | 24630601 |
| Year | 2014 |
| Title | VEGFA activates erythropoietin receptor and enhances VEGFR2-mediated pathological angiogenesis. |
| Drug-related ncRNA | NO |
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